Frank Detorri (Bill Murray) isn't in good health. He lives on junk food, doesn't exercise, and treats his body in every way except as the temple it should be. This unhealthy approach to life turns the inside of Frank's body into a battlefield where bacteria clash. The day he eats a hard-boiled egg he picked up off the floor, we discover that inside Frank lies an organic city full of life and tiny celebrities who imitate human life. When an unknown, deadly disease infects Frank, the unorthodox agent Osmosis Jones (Chris Rock) is sent to investigate it along with the pill Drixenol (David Hyde Pierce). After a constant struggle between bacteria and white blood cells, the body recovers, and Frank realizes he has been mistreating it.
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