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House: Season 5

2008 · 24 episodes · ★ 7.9

What Season 5 of House

Season five opens with Wilson distancing himself from House after a personal tragedy. He leaves his post at the hospital and ends the friendship that once bound them. Meanwhile, the team keeps solving tough cases, such as a dancer with collapsed lungs or a man whose brain houses two personalities. Cameron has to assert her authority over House, and it's no easy task. Thirteen deals with her own medical problems. House, true to form, distrusts the rules and operates on the idea that everyone is hiding something. Hugh Laurie returns to the role in 24 episodes marked by the protagonist's emotional chaos.

24episodes
Sep 16, 2008premiered
May 11, 2009latest episode
17.6 hrtotal runtime

Season 5 Episodes

  1. Dying Changes Everything

    5x01 Dying Changes Everything

    Sep 16, 2008 · 44 min · ★ 7.9

    In the aftermath of personal tragedy, Wilson resigns from the hospital... and from his friendship with House. Meanwhile, Thirteen struggles with her personal medical problems while helping treat an executive assistant with a similar situation to her own.

    Directing: Deran Sarafian · Writing: Eli Attie · Starring: Jamie Rose, Christine Woods, Bob Sherer, Janet Song

  2. Not Cancer

    5x02 Not Cancer

    Sep 23, 2008 · 44 min · ★ 7.7

    The team deals with an organ donor whose organs prove fatal, and the two surviving patients. Meanwhile, House hires a private detective to spy on Wilson, but hears a few things about himself that he'd rather not.

    Directed by: David Straiton · Written by: David Shore, Lawrence Kaplow · Starring: Felicia Day, Tim Conlon, Christine McLain, Jasmine Alvarez

  3. Adverse Events

    5x03 Adverse Events

    Sep 30, 2008 · 44 min · ★ 7.8

    A painter's undiagnosed illness affects his work, and House and his team must look at the man's paintings to determine what's wrong with him.

    Directed by: Andrew Bernstein · Written by: Dustin Paddock, Carol Green · Starring: Breckin Meyer, Marika Domińczyk, Sarah Knowlton, Drew Powell

  4. Birthmarks

    5x04 Birthmarks

    Oct 14, 2008 · 44 min · ★ 8.2

    While en route to his father's funeral, House must help the team with a differential diagnosis on a young Chinese girl who has collapsed under mysterious circumstances.

    Directed by: David Platt · Written by: Doris Egan, David Foster · Starring: Scott Paulin, Jack Conley, Ho-Kwan Tse, Raymond Ma

  5. Lucky Thirteen

    5x05 Lucky Thirteen

    Oct 21, 2008 · 44 min · ★ 7.6

    Thirteen brings her one-night stand to the hospital after the woman has a seizure. However, the woman admits she slept with Thirteen just so she could get to House and have him diagnose her condition. Meanwhile, House continues to pay Lucas to spy on Wilson.

    Directed by: Greg Yaitanes · Written by: Sara Hess, Liz Friedman · Starring: Angela Gots, Helena Barrett, Ali Damji, Michael Weston

  6. Joy

    5x06 Joy

    Oct 28, 2008 · 44 min · ★ 7.6

    An ailing man suffers from blackouts and sleepwalks, leading the team to wonder if his sleepwalking is a symptom, or how the man is becoming exposed to something else. When the man's daughter grows ill as well, the team must provide a diagnosis before both die. Meanwhile, Cuddy adopts a newborn but when the birth mother displays a rash, she has to make a decision between putting the mother or daughter at risk.

    Directed by: Deran Sarafian · Written by: David Hoselton · Starring: Salvator Xuereb, Joanna Koulis, Janice Allen, Bobbin Bergstrom

  7. The Itch

    5x07 The Itch

    Nov 11, 2008 · 44 min · ★ 7.7

    The team must treat an agoraphobic who refuses to leave his house, and have to work around Cuddy, who is less than thrilled at having hospital equipment relocated. Meanwhile, House is plagued by an itch, and Cameron and Chase have relationship issues.

    Directed by: Greg Yaitanes · Written by: Peter Blake · Starring: Todd Louiso, Marcus Eley, Diarra Kilpatrick, Frank Noel

  8. Emancipation

    5x08 Emancipation

    Nov 18, 2008 · 44 min · ★ 7.6

    While Foreman takes on a pediatric case on his own, the rest of the team deals with a 16-year-old factory manager and emancipated minor who collapses at work. When Foreman's patient takes a turn for the worse, he's forced to question whether he can deal with the situation on his own, or if he needs House's help.

    Directed by: James Hayman · Written by: Pam Davis, Leonard Dick · Starring: Nathan Gamble, Liza Colón-Zayas, Emily Rios, Alexandra Lydon

  9. Last Resort

    5x09 Last Resort

    Nov 25, 2008 · 43 min · ★ 8.1

    A gun-wielding man from the waiting room at the Princeton-Plainsboro clinic takes House, Thirteen and several patients from the waiting room hostage in Cuddy's office. The man claims to be sick with a long undiagnosed illness and demands medical attention from the best doctor in the hospital, threatening to kill any hostages necessary along the way.

    Directed by: Katie Jacobs · Written by: Matthew V. Lewis, Eli Attie · Starring: Željko Ivanek, Jack Guzman, Wood Harris, Evan Jones

  10. Let Them Eat Cake

    5x10 Let Them Eat Cake

    Dec 2, 2008 · 44 min · ★ 7.8

    The team takes on the case of a fitness guru on an all-natural diet who collapsed while filming a video. Meanwhile, Foreman conducts Huntington's Disease drug trials and Thirteen signs on as a subject, Cuddy is forced to move into House's office, and Kutner uses House's name to run an online medical-advice website.

    Directing: Deran Sarafian · Writing: Garrett Lerner, Russel Friend · Starring: Samantha Shelton, Danielle Petty, Christopher Stapleton, Julia Putnam

  11. Joy to the World

    5x11 Joy to the World Mid-Season Finale

    Dec 9, 2008 · 44 min · ★ 7.9

    House and his team deal with a bullied girl who collapses during her school's Christmas program. Meanwhile, Foreman and Thirteen grow closer during the Huntington's disease drug trials, House gives a patient a gift, the staff wonder who gave House a special gift, and Cuddy gets an unexpected gift.

    Directing: David Straiton · Writing: Peter Blake · Starring: Taylor Dooley, Meaghan Jette Martin, Elizabeth Tulloch, Sherilyn Fenn

  12. Painless

    5x12 Painless

    Jan 19, 2009 · 44 min · ★ 7.7

    House and the team try to diagnose a man living with severe, chronic pain; Thirteen and Foreman explore their complicated relationship; Cuddy discovers that caring for her baby leaves her with little time to run the hospital.

    Directing: Andrew Bernstein · Writing: Thomas L. Moran, Eli Attie · Starring: James Ingersoll, Aisha Kabia, Bobbin Bergstrom, Anthony Montgomery

  13. Big Baby

    5x13 Big Baby

    Jan 26, 2009 · 44 min · ★ 7.7

    Cuddy decides to spend more time at home to take care of her newly adopted baby and passes some of her day-to-day responsibilities off to Cameron, including supervising House. Cameron is forced to play House’s games and becomes involved in a power struggle as he and the team take on the case of a Special Education teacher who collapsed after spitting up blood in the middle of class. As House tests Cameron’s tolerance for his extreme measures, the patient continues to fall ill and House insists the teacher’s seemingly inherent goodness is actually a pathology.

    Directed by: Deran Sarafian · Written by: Lawrence Kaplow, David Foster · Starring: Bobbin Bergstrom, Erika Flores, Andy Scott Harris, Saige Ryan

  14. The Greater Good

    5x14 The Greater Good

    Feb 2, 2009 · 44 min · ★ 7.7

    House and the team take on the case of a woman who collapsed in the middle of a cooking class, and they soon learn she is a highly-renowned cancer researcher who recently gave up her entire career in order to pursue her own personal happiness. Though the team struggles to understand how the woman could give up saving lives for the sake of her own contentment, each grapple with the pursuit of happiness (or lack thereof) in their own lives. As the patient’s condition continues to worsen, so does Thirteen’s as she begins to suffer serious and life-threatening reactions to the experimental Huntington’s Disease clinical trial. Meanwhile, Cuddy attempts to make House’s life miserable for him in retaliation for his part in her own unhappiness.

    Directed by: Lesli Linka Glatter · Written by: Sara Hess · Starring: Julia Campbell, David Purdham, Jennifer Crystal Foley, Dominic Scott Kay

  15. Unfaithful

    5x15 Unfaithful

    Feb 16, 2009 · 44 min · ★ 7.8

    When a priest who runs a homeless shelter sees a bleeding Jesus hovering at his doorstep, he is admitted to the ER. House takes on the case as a distraction for the team while he confronts Foreman and Thirteen about their relationship. The team soon learns the priest had been involved in a molestation scandal that caused him to lose his faith. However, just as they are about to dismiss his case, the patient’s condition takes a drastic turn for the worse, and House grapples with his past and his belief

    Directed by: Greg Yaitanes · Written by: David Hoselton · Starring: Jimmi Simpson, Jake Thomas, Janet Haley, Terrance Ellis

  16. The Softer Side

    5x16 The Softer Side

    Feb 23, 2009 · 44 min · ★ 7.8

    A patient with both male and female DNA has the team stumped. Meanwhile, House starts acting nicely, raising Cuddy's and Wilson's suspicions that something is terribly wrong.

    Directed by: Greg Yaitanes, Deran Sarafian · Written by: Liz Friedman · Starring: Julia Campbell, Nick Puga, Ben Reed, Nicole Cannon

  17. The Social Contract

    5x17 The Social Contract

    Mar 9, 2009 · 44 min · ★ 8.3

    House and the team take on the case of Nick, a book editor who loses his inhibitions. The team realizes Nick has frontal lobe disinhibition, which causes him to speak his mind having no control over what he says and making him just like House. Meanwhile, House suspects Wilson and Taub are keeping something from him.

    Directing: Andrew Bernstein · Writing: Doris Egan · Starring: Susan Egan, Darcy Rose Byrnes, Jay Karnes, Devon Michaels

  18. Here Kitty

    5x18 Here Kitty

    Mar 16, 2009 · 44 min · ★ 7.8

    Morgan works in a nursing home with a pet cat who only sleeps next to people if they are about to die - and does so with alarmingly accuracy. When it seems the cat has predicted her own death, Morgan, convinced she is about to die, fakes a seizure in order to get to House to have him diagnose her before it’s too late.

    Directing: Juan José Campanella · Writing: Peter Blake · Starring: Judy Greer, Christopher Moynihan, Bob Ross, Charlie Carter

  19. Locked In

    5x19 Locked In

    Mar 30, 2009 · 44 min · ★ 8.4

    A man awakens in New York after a bicycle accident unable to move or communicate in any way. House, himself injured in a motorcycle mishap, occupies the hospital bed next to Lee and quickly annoys the doctors treating them both by insisting that Lee has “locked-in” syndrome.

    Directed by: Dan Attias · Written by: Garrett Lerner, Russel Friend, David Foster · Starring: Skye Barrett, Scotty Noyd Jr., Yasiin Bey, John Kapelos

  20. Simple Explanation

    5x20 Simple Explanation

    Apr 6, 2009 · 44 min · ★ 7.8

    Charlotte, an older woman who has spent the last six months taking care of her dying husband Eddie, is rushed to Princeton Plainsboro after collapsing from respiratory failure. The couple becomes a double mystery for the team when Eddie begins to improve as Charlotte’s condition worsens. The previously unthinkable becomes real when it seems that Charlotte will die before Eddie, and the team will be forced to make a difficult decision.

    Directed by: Greg Yaitanes · Written by: Leonard Dick · Starring: Mary Jo Deschanel, Ed Brigadier, Colleen Camp, Meat Loaf

  21. Saviors

    5x21 Saviors

    Apr 13, 2009 · 44 min · ★ 7.8

    Cameron postpones her vacation with Chase in order to ask House to accept the case of an environmental radical who collapsed at a protest with unexplainable symptoms. Although suspicious of her motives, House agrees. Since she pushed him to take the case so emphatically, House forces Cameron to take the lead and run many of the tests on the patient. Meanwhile, House is unsure of Wilson’s new healthy diet.

    Directed by: Matthew Penn · Written by: Thomas L. Moran, Eli Attie · Starring: Lindsey McKeon, Anne Dudek, Parisa Fakhri, Bruno Oliver

  22. House Divided

    5x22 House Divided

    Apr 27, 2009 · 44 min · ★ 8.4

    The team takes on the case of a deaf 14-year-old named Seth who collapsed after he started “hearing” explosions while competing in a wrestling match. When the team tries to test him for seizures, Seth loses vision in one eye, complicating House’s bunk theory of “Exploding Head Syndrome.” As his condition worsens, the team has an ethical disagreement about the patient and his mother’s adamant decision to forego cochlear implants to supplement his hearing. When the prospect of giving Seth the ability to hear for the first time in his life arises, House and the team are faced with a resounding decision. Meanwhile, House’s lack of sleep starts to play tricks on his mind, but he finds his insomnia may be a gift instead of a burden

    Directed by: Greg Yaitanes · Written by: Liz Friedman, Matthew V. Lewis · Starring: Clare Carey, Anne Dudek, Ryan Lane, Treshelle Edmond

  23. Under My Skin

    5x23 Under My Skin

    May 4, 2009 · 44 min · ★ 8.5

    House and the team take on the case of a ballerina whose lungs collapse in the middle of a performance. When the treatment causes her skin to fall off, the dancer faces not only the prospect of never dancing again but also of dying an agonizing death. The team must use their imaginations to carefully choreograph ways to test and treat her delicate body without killing her. Meanwhile, House continues to suffer from what he thinks is insomnia, and he is willing to go to desperate measures to cure it.

    Directed by: David Straiton · Written by: Pam Davis, Lawrence Kaplow · Starring: Anne Dudek, Jamie Tisdale, Charles Gevoian, Joey Gaynor

  24. Both Sides Now

    5x24 Both Sides Now Season Finale

    May 11, 2009 · 44 min · ★ 8.7

    House and the team are intrigued by Scott, a man whose left brain and right brain operate independently, leaving him with two distinct personalities and no control over some of his actions. As the two sides of Scott’s brain struggle for dominance, his warring personalities make it increasingly difficult for the team to figure out what is causing the unique problem. The team is forced to use some unusual methods to get him to cooperate with their necessary testing. Meanwhile, when House refuses to make an appearance in the clinic, Cuddy takes an unconventional approach to force House to make up the time with a particular patient.

    Directed by: Greg Yaitanes · Written by: Doris Egan · Starring: Carl Reiner, Ashton Holmes, Maria Thayer, Anne Dudek

Season 5 Cast

Omar EppsOmar EppsEric Foreman24 episodes
Bobbin BergstromNurse24 episodes
Jennifer Crystal FoleyJennifer Crystal FoleyRachel Taub4 episodes
Nicole CannonNurse Helen2 episodes
Liz BenoitLiz BenoitNurse Anne2 episodes
Dominic Scott KayDominic Scott KayJackson Smith2 episodes
Jamie RoseJamie RosePatty MichenerEpisode 1
Samantha SheltonSamantha SheltonEmmyEpisode 1
Scott PaulinScott PaulinBobEpisode 1
Felicia DayFelicia DayAppleEpisode 1

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Frequently Asked Questions

How many episodes are in season 5 of House?

House Season 5 has 24 episodes.

When did season 5 of House premiere?

Premiered on September 16, 2008.

Where to watch House Season 5?

In Spain, on Netflix, Movistar Plus+ Ficción Total, SkyShowtime and Netflix Standard with Ads.

What is the best episode of Season 5?

According to the TMDB audience rating, episode 5x24, “Both Sides Now”, with a 8.7.