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Grey's Anatomy: Season 6

2009 · 22 episodes · ★ 8.2

What Season 6 of Grey's Anatomy

Season six begins with the death of George O'Malley, which forces the Seattle Grace staff to come to terms with the loss. Meredith and her fellow residents each cope with the grief in their own way, while the grueling shifts barely leave room for a personal life. The hospital also cuts staff, and the interns compete to keep their jobs. Meanwhile, Meredith faces the chance to save her father Thatcher, who returns to the hospital with a failed liver. Cristina Yang, Izzie Stevens and Alex Karev balance their romantic relationships with their training, under the supervision of Miranda Bailey.

22episodes
Sep 24, 2009premiered
May 20, 2010latest episode
17.2 hrtotal runtime

Season 6 Episodes

  1. Good Mourning; Goodbye

    6x01 Good Mourning; Goodbye

    Sep 24, 2009 · 86 min · ★ 8.3

    The hospital staff is left to deal with the aftermath of George's passing. Hitting the staff hard, they all find unique ways to get through the various stages of grief. George's mom returns, faced with the difficult task of deciding what to do with his organs.Everyone is struggling after losing one of their own and are turning to any distraction they can find. Meredith and Derek seem to be consummating their marriage anywhere and everywhere, while Cristina and Owen have been instructed to abstain from sex by Dr. Wyatt.

    Directed by: Bill D'Elia, Edward Ornelas · Written by: Krista Vernoff · Starring: T.J. Lowther, Gloria Garayua, Mitch Pileggi, Mark Saul

  2. I Always Feel Like Somebody's Watchin' Me

    6x03 I Always Feel Like Somebody's Watchin' Me

    Oct 1, 2009 · 43 min · ★ 7.9

    Several weeks after her near-death experience, a recovering Izzie returns to work. Meanwhile, nervous that there will be layoffs in the hospital in the wake of an announcement from the Chief, the Seattle Grace residents compete to survive the cuts, including Cristina, who attempts to work alongside Arizona in pediatrics. And Bailey and Alex's patient's already complex case is further complicated by her schizophrenic son.

    Directed by: Michael Pressman · Written by: Joan Rater · Starring: Gloria Garayua, Mark Saul, Sarah Utterback, James Frain

  3. Tainted Obligation

    6x04 Tainted Obligation

    Oct 8, 2009 · 43 min · ★ 7.9

    When Meredith and Lexie's father, Thatcher, returns to the hospital with a failed liver, it's up to Meredith to save his life. Meanwhile, Izzie empathizes with a patient riddled with tumors, as Mark, annoyed with Cristina's competitive zeal, tricks her into assisting on an unusual surgery.

    Directed by: Tom Verica · Written by: Jenna Bans · Starring: Jeff Perry, Mark Saul, Tom Amandes, Isabella Hofmann

  4. Invasion

    6x05 Invasion

    Oct 15, 2009 · 43 min · ★ 7.9

    The residents of Seattle Grace and Mercy West vie for surgeries and their careers as day one of the hospital merger begins. Meanwhile, Arizona stands by an enraged Callie when her father, Mr. Torres, employs a priest to help convince her to date men, and Izzie experiences the brunt of her new surgical competition.

    Directed by: Tony Phelan · Written by: Mark Wilding · Starring: Jesse Williams, Sarah Drew, Héctor Elizondo, Gloria Garayua

  5. I Saw What I Saw

    6x06 I Saw What I Saw

    Oct 22, 2009 · 43 min · ★ 8.6

    After a burn victim unexpectedly dies in the midst of a chaotic ER, the Chief and board member Jennings interrogate the residents to find the culprit, as all the Mercy West and Seattle Grace resident defends their actions in an effort to save their jobs.

    Directed by: Allison Liddi-Brown · Written by: William Harper · Starring: Jesse Williams, Sarah Drew, Moe Irvin, Nora Zehetner

  6. Give Peace a Chance

    6x07 Give Peace a Chance

    Oct 29, 2009 · 43 min · ★ 8.5

    When Isaac has an inoperable tumor wrapped around his spine, he wants Derek to do the impossible. Derek tests the Chief's authority when Richard objects to moving forward with the risky surgery.

    Directing: Chandra Wilson · Writing: Peter Nowalk · Starring: Jesse Williams, Nora Zehetner, Mark Saul, Faran Tahir

  7. Invest In Love

    6x08 Invest In Love

    Nov 5, 2009 · 43 min · ★ 8.2

    A generous 25 million donation is offered to Seattle Grace by the parents of Arizonas 10-year-old patient, she finds herself in a conflict of interest when his condition worsens. Cristina tests her boundaries with Owen at the hospital. Alex is left with all of Izzies hospital bills to contend with.

    Directed by: Jessica Yu · Written by: Stacy McKee · Starring: Jesse Williams, Alanna Masterson, Nora Zehetner, Mitch Pileggi

  8. New History

    6x09 New History

    Nov 12, 2009 · 43 min · ★ 8.1

    Owen recruits Dr. Teddy Altman, a former Iraqi veteran, as the new cardiothoracic surgeon. Cristina questions her abilities in the E.R. and relationship with Owen. Izzie returns to Seattle Grace with her high school mentor seeking treatment for his dementia. Richard's responsibilities, post-merger, are taking a toll on him.

    Directed by: Rob Corn · Written by: Allan Heinberg · Starring: Jesse Williams, Loretta Devine, Steven W. Bailey, Nora Zehetner

  9. Holidaze

    6x10 Holidaze Mid-Season Finale

    Nov 19, 2009 · 43 min · ★ 7.9

    As Thanksgiving, Christmas and New Year's pass, Miranda gets a visit from her father, William who disapproves of her choices in life. Mark and Lexie cope with an arrival of a woman from his past. Thatcher questions the Chief's recent behavior as Meredith comes to his defense.

    Directed by: Robert Berlinger · Written by: Krista Vernoff · Starring: Jesse Williams, Jeff Perry, Danielle Panabaker, Steven W. Bailey

  10. Blink

    6x11 Blink

    Jan 14, 2010 · 43 min · ★ 8.1

    Mark flies Addison to Seattle to help with a difficult procedure on his pregnant daughter, Sloan, Owen questions Teddy's motives when she assigns Cristina the lead on a complicated surgery, and Derek's suspicions are raised when the Chief recruits Meredith to assist with a high profile operation on.

    Directed by: Randall Zisk · Written by: Debora Cahn · Starring: Kate Walsh, Leven Rambin, Nora Zehetner, Cynthia Stevenson

  11. I Like You So Much Better When You're Naked

    6x12 I Like You So Much Better When You're Naked

    Jan 21, 2010 · 43 min · ★ 7.8

    After learning of Richard's drinking problem, Derek confronts him for the sake of his friend and the hospital, Izzie returns, hoping to reconcile with Alex, and tensions run high between Teddy, Cristina and Owen in the aftermath of Cristina's startling confession.

    Directed by: Donna Deitch · Written by: Joan Rater · Starring: Jesse Williams, Moe Irvin, Paul Vogt, Dan Bucatinsky

  12. State of Love and Trust

    6x13 State of Love and Trust

    Feb 4, 2010 · 43 min · ★ 7.9

    As Derek begins his role as interim chief, he faces a potential lawsuit when Bailey and Meredith's patient awakens from anesthesia mid-surgery. Meanwhile, Teddy refuses to place Cristina on her service, as Arizona tests Alex out in Pediatrics, and Mark refuses to speak to a heartbroken Lexie.

    Directing: Jeannot Szwarc · Writing: Stacy McKee · Starring: Jason George, Jesse Williams, Sarah Drew, Cody Christian

  13. Valentine's Day Massacre

    6x14 Valentine's Day Massacre

    Feb 11, 2010 · 43 min · ★ 8.0

    It's Valentine's Day, and the doctors must treat dozens of injured people after the roof collapses at a popular romantic restaurant; Derek tries to manage his busy schedule as Chief of Surgery; Meredith wrestles with her new duties as the Chief's wife; and Mark and Callie team up to convince Sloan to do the right thing for her baby.

    Directing: Stephen Cragg · Writing: William Harper · Starring: Jason George, Jesse Williams, Sarah Drew, Leven Rambin

  14. The Time Warp

    6x15 The Time Warp

    Feb 18, 2010 · 43 min · ★ 8.6

    In his new role as Chief, Derek restores the hospital lecture series, and Richard, Bailey and Callie present to the group pivotal surgical cases from their pasts Bailey reflects on her first days as a shy resident, Callie looks back on a polio case, and Richard recalls a case in which he and Ellis worked on a patient diagnosed with GRID, a virus later called AIDS.

    Directed by: Rob Corn · Written by: Zoanne Clack · Starring: Jason George, Jesse Williams, Steven W. Bailey, Sarah Paulson

  15. Perfect Little Accident

    6x16 Perfect Little Accident

    Mar 4, 2010 · 43 min · ★ 8.2

    When famous surgeon Dr. Harper Avery is rushed to Seattle Grace-Mercy West, the staff is surprised to discover that one of their own is related to this legend, and his unorthodox request for his surgery causes tensions t between Derek and Richard. Meanwhile Callie and Arizona try to help Teddy and Sloan move on from their pasts and find greener pastures.

    Directing: Bill D'Elia · Writing: Peter Nowalk · Starring: Jesse Williams, Tess Harper, Chelcie Ross, Robert Baker

  16. Push

    6x17 Push

    Mar 11, 2010 · 43 min · ★ 8.3

    A patient who needs an extremely difficult surgery comes to Seattle Grace, and it's Richard and Owen who vie for the opportunity to tackle it. But the decision lies in the hands of Derek, who deems that Owen should take on the surgery, leaving Richard bitter. Meanwhile, Bailey deals with her own personal struggles when she nervously prepares for another date with Ben.

    Directed by: Chandra Wilson · Written by: Debora Cahn · Starring: Jason George, Jesse Williams, Diane Venora, Dennis Boutsikaris

  17. Suicide Is Painless

    6x18 Suicide Is Painless

    Mar 25, 2010 · 43 min · ★ 8.1

    When Teddy's patient seeks to end treatment and her life, she turns to Hunt for help. The situation triggers Hunt's memories of his life at war and his past relationship with Teddy. Meanwhile, Callie and Arizona have a difference in opinion on what their future holds, and Richard tries to adjust to his role as a surgeon.

    Directed by: Jeannot Szwarc · Written by: Joan Rater · Starring: Jesse Williams, Sarah Drew, Richard T. Jones, Sara Gilbert

  18. Sympathy for the Parents

    6x19 Sympathy for the Parents

    Apr 1, 2010 · 43 min · ★ 8.0

    When Alex's younger brother, Aaron, shows up at Seattle Grace-Mercy West with a hernia, it's up to Alex to get Bailey's approval for his pro bono surgery. Matters are further complicated when Aaron discloses that his family has not heard from Alex since he arrived in Seattle, and parts of Alex's past long kept secret are revealed to his friends and fellow doctors.

    Directing: Debbie Allen · Writing: Allan Heinberg · Starring: Jesse Williams, Sarah Drew, Leven Rambin, Michael O'Neill

  19. Hook, Line and Sinner

    6x20 Hook, Line and Sinner

    Apr 29, 2010 · 43 min · ★ 7.8

    Sloan returns to Mark's apartment, just as she's going into labor, and Teddy, Mark and the still-fighting Callie and Arizona are there to help with the birth and to get Mark through his grandson's pending adoption. Meanwhile Teddy sees Derek's invitation to illustrious cardiothoracic surgeon Tom Evans' as a threat to her future employment at the hospital, and the team work on a crab boat captain who has been stabbed with a giant shark hook.

    Directed by: Tony Phelan · Written by: Meg Marinis · Starring: Jesse Williams, Sarah Drew, Leven Rambin, Nicholas Purcell

  20. How Insensitive

    6x21 How Insensitive

    May 6, 2010 · 43 min · ★ 8.2

    Bailey preps the team with mandatory sensitivity training prior to admitting a 700-pound patient with compounded medical issues, and the case proves to be challenging in every sense of the word. Meanwhile Derek has to come face to face with a former patient's husband in a wrongful death deposition, and spending time with a heart patient's daughter opens up some old wounds for Cristina.

    Directed by: Tom Verica · Written by: Shonda Rhimes, Peter Nowalk · Starring: Jesse Williams, Sarah Drew, Michael O'Neill, Nora Zehetner

  21. Shiny Happy People

    6x22 Shiny Happy People

    May 13, 2010 · 43 min · ★ 8.3

    An elderly patient admitted into the E.R. for a heart condition sees a familiar face, a long lost love who happens to be in the E.R. as well for a fractured arm, and the staff find themselves caught up in their love story. Meanwhile, Karev treats a troubled teenage patient (guest star Demi Lovato) whose parents brought her in for schizophrenia, and Meredith can't help but tell Cristina about her suspicions of Owen -- which inevitably messes with Cristina's head.

    Directed by: Edward Ornelas · Written by: Zoanne Clack · Starring: Jason George, Jesse Williams, Sarah Drew, Demi Lovato

  22. Sanctuary; Death and All His Friends

    6x23 Sanctuary; Death and All His Friends Season Finale

    May 20, 2010 · 86 min · ★ 9.1

    Seattle Grace Hospital is hit with a crisis like no other in its history.Cristina and Meredith's surgical skills are put to the ultimate test.

    Directing: Rob Corn, Stephen Cragg · Writing: Shonda Rhimes · Starring: Jesse Williams, Sarah Drew, Ryan Devlin, Gloria Garayua

Season 6 Cast

Ellen PompeoEllen PompeoMeredith Grey22 episodes
Chandra WilsonChandra WilsonMiranda Bailey22 episodes
Kevin McKiddKevin McKiddOwen Hunt22 episodes
Sara RamirezSara RamirezCallie Torres22 episodes
Jessica CapshawJessica CapshawArizona Robbins22 episodes
Jesse WilliamsJesse WilliamsJackson Avery18 episodes
Sarah DrewSarah DrewApril Kepner10 episodes
Nora ZehetnerNora ZehetnerReed Adamson10 episodes
Mark SaulMark SaulSteve8 episodes
Jason GeorgeJason GeorgeBen Warren5 episodes
Leven RambinLeven RambinSloan Riley5 episodes
Gloria GarayuaGloria GarayuaIntern Graciella5 episodes
Moe IrvinMoe IrvinNurse Tyler Christian5 episodes
Steven W. BaileySteven W. BaileyJoe3 episodes

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Frequently Asked Questions

How many episodes does Season 6 of Grey's Anatomy have?

Season 6 of Grey's Anatomy has 22 episodes.

When Did Season 6 of Grey's Anatomy Premiere?

Premiered on September 24, 2009.

Where to Watch Season 6 of Grey's Anatomy?

In Spain, on Disney Plus.

What is the best episode of Season 6?

According to the TMDB audience rating, episode 6x23, «Sanctuary; Death and All His Friends», with a 9.1.