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Grey's Anatomy: Season 2

2005 · 27 episodes · ★ 8.5

What Season 2 of Grey's Anatomy

The second season opens with the interns at Seattle Grace Hospital in their second year, when the shifts are still exhausting and leave little room for personal life. Meredith watches her relationship with Derek grow complicated with the arrival of Addison, his wife. Cristina must handle medical cases on her own, while Alex reveals his obsession with Izzie. George is torn between Olivia and the feelings he still has for Meredith. Everything unfolds under the supervision of Miranda Bailey, while Dr. Webber recovers from his surgery.

27episodes
Sep 25, 2005premiered
May 15, 2006latest episode
19.4 hrtotal runtime

Season 2 Episodes

  1. Raindrops Keep Falling on My Head

    2x01 Raindrops Keep Falling on My Head

    Sep 25, 2005 · 43 min · ★ 8.6

    Picks up where the last episode left off. Meredith attempts to work with Addison Shepard. George is pimped out to relay the hospital gossip back to Webber. Meredith and Cristina relate at Emerald City Bar about what dating their respective attendings is like. Cristina ponders her relationship with Burke while trying to make a decision. Meredith is devastated by the latest blow to her love life. Meanwhile, Joe the bartender collapses.

    Directed by: Peter Horton · Written by: Stacy McKee · Starring: Steven W. Bailey, Noelle McCutchen, Wendy Gazelle, Robin Pearson Rose

  2. Enough Is Enough

    2x02 Enough Is Enough

    Oct 2, 2005 · 43 min · ★ 8.4

    There's tension between Meredith and Addison. We find out why Derek and Addison aren't together. Bailey puts George on an impossible case. The rest of the interns operate on a family that was just in a car accident.

    Directing: Peter Horton · Writing: James D. Parriott · Starring: Loretta Devine, Lukas Behnken, Romy Rosemont, Scott Michael Campbell

  3. Make Me Lose Control

    2x03 Make Me Lose Control

    Oct 9, 2005 · 43 min · ★ 8.2

    Cristina and Meredith try to figure out if Cristina should tell Burke that she's pregnant right before Cristina faces an emergency. Alex and Izzie get closer while Meredith's mother gets too close.

    Directed by: Adam Davidson · Written by: Krista Vernoff · Starring: Angela Goethals, Noelle McCutchen, Jeremy Rabb, Linda Klein

  4. Deny, Deny, Deny

    2x04 Deny, Deny, Deny

    Oct 16, 2005 · 43 min · ★ 8.7

    As Cristina tries to recover, she proves to be a very difficult patient, and a visit from her mother doesn't improve her demeanor any. And Meredith's mother, Dr. Ellis Grey, has the hospital staff running in circles.

    Directing: Wendey Stanzler · Writing: Zoanne Clack · Starring: Thomas Ian Nicholas, Lee Garlington, Katherine LaNasa, Steven W. Bailey

  5. Bring the Pain

    2x05 Bring the Pain

    Oct 23, 2005 · 43 min · ★ 8.6

    Cristina goes right back to working right after being discharged. Izzie isn't talking to Alex. Derek and Meredith treat a patient. George and Alex get stuck in an elevator.

    Directing: Mark Tinker · Writing: Shonda Rhimes · Starring: Michelle Krusiec, Mimi Kennedy, Daniel Bess, Steven W. Bailey

  6. Into You Like a Train

    2x06 Into You Like a Train

    Oct 30, 2005 · 43 min · ★ 9.1

    Train Wreck victims come to Seattle Grace and all staff gets called in. Everyone deals with really weird cases. Except Addison and Izzie. They work with a woman who is pregnant.

    Directing: Jeff Melman · Writing: Krista Vernoff · Starring: Bruce A. Young, Kym Whitley, Michelle Arthur, Cynthia Ettinger

  7. Something to Talk About

    2x07 Something to Talk About

    Nov 6, 2005 · 43 min · ★ 8.5

    Cristina, Izzie and Meredith take care of Shane, a man who appears to be crazy and claims that he is pregnant. Shane's case induces a spreading fascination among the staff. George relates to a patient's husband.

    Directing: Adam Davidson · Writing: Stacy McKee · Starring: Tyrees Allen, Reni Santoni, Steven W. Bailey, Kerry Carney

  8. Let It Be

    2x08 Let It Be

    Nov 13, 2005 · 43 min · ★ 8.3

    Meredith tries to avoid the Shepherds. Cristina and Burke go out on a date and end up getting caught up in their jobs. Derek asks Meredith not to ignore him until Addison comes walking around the corner.

    Directed by: Lesli Linka Glatter · Written by: Mimi Schmir · Starring: Arija Bareikis, Shelley Berman, Joseph Lyle Taylor, Geoffrey Rivas

  9. Thanks for the Memories

    2x09 Thanks for the Memories

    Nov 20, 2005 · 43 min · ★ 8.6

    It's Thanksgiving at Seattle Grace Hospital but the holiday's festivites are less than in order. Meredith and Derek try to counsel a family after their relative has had a seriously traumatic accident.

    Directed by: Michael Dinner · Written by: Shonda Rhimes · Starring: Brian Kerwin, Greg Pitts, Andrew James Allen, George Dzundza

  10. Much Too Much

    2x10 Much Too Much

    Nov 27, 2005 · 43 min · ★ 8.2

    Dorie Russell is waiting for quintuplets, all 5 girls. Her husband seems more concerned than she is but she is set to bring her babies to their term of 36 weeks. All the departments are on call for the quintuplets as three of them have developped problems of different kinds. Meredith last night's stand shows up at the hospital with priapism and they need to call Derek Sheperd for a consult which puts Meredith in a very embarassing position. Alex and Derek must take care of a patient who has a tumor inducing thirst as a side effect. On the love side, Alex and Izzie are having some slight sexual problems, while Meredith goes on adding one night stands and Cristina is thrown off course by being "keyed."

    Directing: Wendey Stanzler · Writing: Gabrielle Stanton, Harry Werksman · Starring: Curtis Armstrong, Sunkrish Bala, Jon Hershfield, Margaret Welsh

  11. Owner of a Lonely Heart

    2x11 Owner of a Lonely Heart

    Dec 4, 2005 · 43 min · ★ 8.3

    Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

    Directing: Daniel Minahan, Chandra Wilson · Writing: Mark Wilding · Starring: Curtis Armstrong, Rosanna Arquette, Timothy Bottoms, Patricia Bethune

  12. Grandma Got Run Over By a Reindeer

    2x12 Grandma Got Run Over By a Reindeer Mid-Season Finale

    Dec 11, 2005 · 43 min · ★ 8.4

    The holiday season has started but not everyone is in a festive mood. This is Alex's last day in the hospital unless he passes his boards practical exam the next day, thus everyone helps him to review so that he succeeds. However, Izzie is not happy about the others helping him and Meredith has to remind her of the true spirit of the Christmas holiday. Justin is in need of a new heart. One is available but he does not want it because he does not believe Santa gave it to him as his mother said. Cristina and Burke, both handling Justin's case, have opposing views on the matter due to their different stances on religion. Despite a reconciliation with his wife, Derek isn't in a festive mood. George has a simple case of a woman who has a bleeding ulcer, he realizes that the ulcer is caused by her entourage but fails to keep them away, with the consequence that it perforates.

    Directing: Peter Horton · Writing: Krista Vernoff · Starring: Helen Slater, C.J. Sanders, Michael Hyatt, Steven W. Bailey

  13. Begin the Begin

    2x13 Begin the Begin

    Jan 15, 2006 · 43 min · ★ 8.6

    Cristina is bothered by a new year's mandatory work limit. Izzie patient, Denny Duquette, wants two things: 1. a heart transplant, 2. Izzie. Addison detests Derek's trailer, Derek visits Meredith's mom, George treats a young teen hermaphrodite frustrated by her pre-pubescence. Other news includes patients doing uncanny things and relationship havoc being wrecked between the doctors, as per usual.

    Directed by: Jessica Yu · Written by: Kip Koenig · Starring: Lauren Tom, Shannon Cochran, Stephen Spinella, John Prosky

  14. Tell Me Sweet Little Lies

    2x14 Tell Me Sweet Little Lies

    Jan 22, 2006 · 43 min · ★ 8.4

    Meredith and Cristina lie to each other and themselves about their relationships with McDreamy and Burke, respectively. George is given a hard task to expel a discharged and defiant woman from the hospital. Alex learns his fate after re-taking his medical exams. At the same time Izzie is trying to stop Alex from making stupid decisions when a patient that doesn't speak English is lied to by her coach. George, Cristina, and Alex compete in a hot dog eating competition.

    Directing: Adam Davidson · Writing: Joan Rater · Starring: Donovan Leitch, Carole Cook, Jill Holden, Christopher Boyer

  15. Break on Through

    2x15 Break on Through

    Jan 29, 2006 · 43 min · ★ 8.7

    All the nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves. George refuses to cross the picket line and finally joins the nurses on their strike while Alex, Cristina, Izzie and Meredith meets Bailey's stand-in: Dr. Cindy Aaron, the complete opposite of Miranda Bailey. Izzie agrees to work on a difficult pregnancy case with Addison, while Cristina and Alex are in the pit attending to a young married woman with a real bad case of rash. Meredith happens on an old woman that she needs to intubate and then learns she was DNR.

    Directing: David Paymer · Writing: Zoanne Clack · Starring: Steven W. Bailey, Robin Pearson Rose, Jeremy Rabb, Cathy Lind Hayes

  16. It's the End of the World

    2x16 It's the End of the World

    Feb 5, 2006 · 43 min · ★ 9.1

    An explosive case arrives at the O.R. that might endanger all the lives of the people working there, which leads Dr. Burke to declare a "Code Black" for the hospital. Bailey worries where her husband is as she is in labor. Also Izzie and Alex may be creating some heat.

    Directing: Peter Horton · Writing: Shonda Rhimes · Starring: Kyle Chandler, Cress Williams, Kathleen M. Darcy, Cathy Lind Hayes

  17. As We Know It

    2x17 As We Know It

    Feb 12, 2006 · 43 min · ★ 9.2

    Derek is still operating when he finds out about Meredith's current situation. Meredith is freaking out about her situation. Webber and Bailey are dealing with medical health issues. Cristina and Izzie have their own issues to deal with because of Meredith's situation. Addison freaks out when George tries to find a solution to Bailey's impromtu postponement. Overall, Seattle Grace Hospital is still under code black and the situation is getting worse.

    Directing: Peter Horton · Writing: Shonda Rhimes · Starring: Loretta Devine, Kyle Chandler, Cress Williams, Kathleen M. Darcy

  18. Yesterday

    2x18 Yesterday

    Feb 19, 2006 · 43 min · ★ 8.3

    Derek and Addison's relationship is rocked to the core when a former friend comes to Seattle Grace and his presence promises to shake things up for a few members of the staff. Burke and Cristina's relationship is affected when one of her secrets is outted. Alex and Izzie are having similar reactions to their closet scenes during the Code Black crisis. On top of this a cocky doctor shows up to piss Derek off in all kinds of ways. A patient is suffering from constant orgasms and her condition sparks interesting conversations among the staff. George is trying to figure out how to get Meredith to see him as more than just a housemate. Another patient, that Derek is treating, is dealing with a rare disorder and needs his parents support and understanding. Burke has a patient who inspires him to talk to Meredith and Cristina about doing what they say they will. Meanwhile, Meredith learns more about her family (in fact maybe more than she may have wanted to know) through her parents.

    Directed by: Rob Corn · Written by: Krista Vernoff · Starring: Eric Dane, Jeff Perry, Jesse Plemons, Steven W. Bailey

  19. What Have I Done to Deserve This?

    2x19 What Have I Done to Deserve This?

    Feb 26, 2006 · 43 min · ★ 8.6

    Meredith and George are experiencing morning-after tension at home and at work and it has the rest of the doctors wondering what's up. Derek and Addison are experiencing their own version of morning-after tension as a result of Mark's visit to Seattle. Bailey, returning the favor that was done for her during the Code Black situation, must treat Addison for a specific feminine problem. Izzie and Alex are making headway in their relationship until Denny Duquette comes back. Soon Alex is not-so-oddly jealous of the attention Izzie is showing to Denny. Someone finds comfort in confiding in a patient who is going through an ordeal of his own. Burke deals with a patient and gets to observe the patient's unstable relationship with his fiancée.

    Directed by: Wendey Stanzler · Written by: Stacy McKee · Starring: Sara Ramirez, Matt Roth, Mark Harelik, Cress Williams

  20. Band-Aid Covers the Bullet Hole

    2x20 Band-Aid Covers the Bullet Hole

    Mar 12, 2006 · 43 min · ★ 8.4

    The doctors are up to their necks in their usual levels of drama. Meredith is dealing with the backlash of sleeping with George, George and Burke are bonding in ways that bother and creep out Cristina, Cristina gets stuck on diaper duty, Bailey gets involved in a case even though she's still supposed to be on maternity leave, Addison and Derek have a talk, and Izzie is still flaking on Alex for Denny Duquette, the heart patient who didn't get a heart. In the patients-of-the-week department we've got a very pregnant woman, a hockey player who desires medically unnessasary amputation, and a woman with a fork in her neck who happens to be dying and has a struggling marriage.

    Directing: Julie Anne Robinson · Writing: Gabrielle Stanton, Harry Werksman · Starring: Sara Ramirez, Teddy Dunn, Natalie Cole, Stephen Lee

  21. Superstition

    2x21 Superstition

    Mar 19, 2006 · 43 min · ★ 8.0

    After a series of deaths at the hospital some of the staff become very superstitious. Izzie worries about Denny and gets confronted by Alex. A patient with OCD drives Cristina crazy. Derek and Addison discuss their relationships with Meredith. Richard treats a friend from 17 years ago who reveals a secret about a dark time in his past that involves Ellis. George gets an earful about the women he's not talking to. Burke and Cristina argue about kicking George out.

    Directing: Tricia Brock · Writing: James D. Parriott · Starring: Sara Ramirez, Kerry Carney, Kathleen M. Darcy, Keeshan Giles

  22. The Name of the Game

    2x22 The Name of the Game

    Apr 2, 2006 · 43 min · ★ 8.4

    Meredith and Izzie take up knitting. Derek operates on Andrew, a spelling bee champ with a serious head injury. Bailey gets in on Andrew's surgery because she's worried that her coworkers won't recognize her Nazi-status now that she's a mother. Addison's patient has an unborn baby with medical issues. After Alex fails to bite his tongue when a terminal patient routinely lies to her daughter about her health he gets a lesson in bedside manners from Burke. George also begins to overstay his welcome at Burke's apartment after Callie visits him. Meredith has more confusing and uncomfortable encounters with members of her family. One of the female doctors meets a veterinarian named Finn. Izzie flirts with Denny and they play more naughty-Scrabble. Meredith, Derek, and Addison sarcastically take another small stab at their friendships.

    Directed by: Seith Mann · Written by: Shonda Rhimes, Blythe Robe · Starring: Sara Ramirez, Chris O'Donnell, Jeff Perry, Steven W. Bailey

  23. Blues for Sister Someone

    2x23 Blues for Sister Someone

    Apr 30, 2006 · 43 min · ★ 8.3

    Addison's patient is a Catholic mother of seven. Addison gets in trouble after learning that the patient's husband won't use contraceptives. Derek treats a divorce attorney who asks if Derek is in need of her services. While Izzie and George are talking about their personal lives they "overhear" part of Derek's conversation with the divorce attorney who calls herself one of Seattle's best. Alex gets in trouble with Addison yet again for not being able to keep his mouth shut when other people think he should. A legendary jazz musician refuses to see medical reason. The musician is Burke's musical hero. Finn makes Meredith breakfast.

    Directing: Jeff Melman · Writing: Shonda Rhimes, Elizabeth J.B. Klaviter · Starring: Sara Ramirez, Chris O'Donnell, Noelle McCutchen, Kathleen M. Darcy

  24. Damage Case

    2x24 Damage Case

    May 7, 2006 · 43 min · ★ 8.6

    The staff attends to an intern from another hospital who has short-term memory loss. This intern, named Marshall, also has caused a car accident that involved a married couple, their unborn baby and the woman's parents who the staff are also treating. The pregnant woman is named Melanie and she will die but her baby may survive. One of the female interns meets up with a woman from her past who is planning on having a family of her own. Cristina is in a good mood although Alex, Izzie, George, and Meredith are having problems but in the meantime Burke hasn't forgiven Cristina for her late night faux pas. Meredith and Izzie are making fun of Callie's household habits and George and Callie are having a fight because of George's roommates. Addison is continuing to own Alex and he's upset about it. Denny has an outburst at Izzie and Derek has an outburst at Meredith.

    Directed by: Tony Goldwyn · Written by: Mimi Schmir · Starring: Sara Ramirez, Chris O'Donnell, Maile Flanagan, Frances Fisher

  25. 17 Seconds

    2x25 17 Seconds

    May 14, 2006 · 43 min · ★ 8.9

    George and Derek work together, Denny still doesn't have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and her parents try to keep the baby alive. This causes tension between Derek and Addison. One doctor's overreaction unites two bickering patients. Finn is still treating Doc for medical problems.

    Directing: Daniel Minahan · Writing: Mark Wilding · Starring: Sara Ramirez, Brooke Smith, Chris O'Donnell, Steven W. Bailey

  26. Deterioration of the Fight or Flight Response

    2x26 Deterioration of the Fight or Flight Response

    May 15, 2006 · 43 min · ★ 8.6

    Denny needs a heart or else. Izzie and George go crazy trying to get him one. Derek has the life of a friend in his hands as he operates on Burke who has been shot. Burke cannot operate on Denny after Denny's heart stopped and now Denny is in a dire condition. Cristina gets put in charge of the ER and she is worried about Burke.

    Directed by: Rob Corn · Written by: Joan Rater · Starring: Brooke Smith, Loretta Devine, Jeremy Rabb, Sarah Utterback

  27. Losing My Religion

    2x27 Losing My Religion Season Finale

    May 15, 2006 · 43 min · ★ 8.5

    This episode is the second part of a two-hour season finale. Richard tries to get information from Addison about a family member's condition. Callie and George have a talk about his feelings. Meredith and Derek have a talk about Doc.

    Directing: Mark Tinker · Writing: Shonda Rhimes · Starring: Sara Ramirez, Brooke Smith, Chris O'Donnell, Sarah Utterback

Season 2 Cast

Ellen PompeoEllen PompeoMeredith Grey27 episodes
Chandra WilsonChandra WilsonMiranda Bailey27 episodes
Kate WalshKate WalshAddison Montgomery27 episodes
Steven W. BaileySteven W. BaileyJoe11 episodes
Sarah UtterbackSarah UtterbackOlivia Harper9 episodes
Linda KleinLinda KleinNurse Linda9 episodes
Sara RamirezSara RamirezCallie Torres8 episodes
Robin Pearson RosePatricia Murphy8 episodes
Kathleen M. DarcyKathleen M. DarcyAnesthesiologist8 episodes
Jeremy RabbJeremy RabbResident7 episodes
Cathy Lind HayesCathy Lind HayesNurse Debbie6 episodes
Moe IrvinMoe IrvinNurse Tyler Christian5 episodes
Ray FordRay FordParamedic Ray5 episodes
Noelle McCutchenNurse Vivian4 episodes

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Frequently Asked Questions

How many episodes does Season 2 of Grey's Anatomy have?

Season 2 of Grey's Anatomy has 27 episodes.

When Did Season 2 of Grey's Anatomy Premiere?

Premiered on September 25, 2005.

Where to Watch Season 2 of Grey's Anatomy?

In Spain, on Disney Plus.

What is the best episode of Season 2?

According to the audience rating on TMDB, episode 2x17, "As We Know It," with a 9.2.